| IWA Publishing Journals | | | Subscriptions | | | Authors | | | Users | | | Librarians | | | FAQs |
 |
Journal of Water and Health Vol 08 No 1 pp 139–146 © IWA Publishing 2010 doi:10.2166/wh.2009.018 Risks of childhood cancer among Texas watersheds, based on mothers' living locations at the time of birthJames A. Thompson, Susan E. Carozza, Wesley T. Bissett and Li ZhuDepartment of Large Animal Clinical Science, Texas A&M University, College Station TX, 77843-4475, USA Tel.:Department of Epidemiology and Biostatistics, School of Rural Public Health, Texas A&M University, College Station TX, 77843, USA ABSTRACT Cancer is the most common fatal disease among US children. The fetus has reduced resistance to toxic injury and is especially prone to mutagenic injury because of the high rate of cell division. A fetus can be exposed to environmental toxins through maternal consumption of contaminated water. The objective of this study was to estimate the incidence risk for childhood cancers within each watershed in Texas. The approach modeled risk for 19 cancer histotypes incorporating correlations among the cancer types and spatial correlation. Several watersheds in a very large area known as the Central Great Plains of North Texas were associated with increased risk for astrocytoma. Two watersheds near Houston, Buffalo–San Jacinto and West Galveston Bay, had increased risk for renal cancer and acute lymphoid leukemia, respectively. A watershed in South Texas, the South Laguna Madre, had increased risk for atypical leukemias. The possibility that waterborne toxins cause these childhood cancers should be investigated further. Keywords: childhood cancer; model; multivariate; spatial; watersheds eProduct: Buy this article for £24.00 (IWA MEMBER PRICE: £18.00) All prices include VAT. For customers where VAT should not be applied, the VAT amount will be removed upon payment |
|
 |
